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Current Rheumatology Reports , 26 (12), 403413
When tested as a once-daily injection in single and multiple doses varying up to 0.18 mg in healthy normal to overweight volunteers, gastrointestinal adverse events (nausea, diarrhoea, constipation, vomiting) were encountered, but the drug was described as well tolerated
In addition to working with your doctor to come off the drug, Kessler recommends a high-protein diet, because protein replicates the feelings of satiety you get from a GLP-1 drug, and may help you to sustain a lower weight
This brings us, you mentioned about the Parkinson's, and when I reviewed the three randomized Parkinson's trials, they're all small, but it appears to be the first disease modifying drug ever in Parkinson's